929Comparison of Echinocandin vs Amphotericin B Based Therapy for Candida Infective Endocarditis: An Observational Cohort Study
نویسندگان
چکیده
Candida Infective Endocarditis: An Observational Cohort Study Christopher Arnold, MD; Melissa Johnson, PharmD; Suzanne Bradley, MD, FIDSA, FSHEA; Efthymia Giannitsioti, MD, ID; Nuria Fernandez-Hidalgo, MD; Pierre Tattevin; Jacob Strahilevitz, MD; Denis Spelman, MBBS FRACP FRCPA MPH; Eugene Athan, MBBS, FRACP, MPH; Francisco Nacinovich, MD; Cristiane Lamas, MD, PhD; Vivian Chu, MD; Duke University Medical Center, Durham, NC; Internal Medicine, University of Michigan and Ann Arbor VA Healthcare System, Ann Arbor, MI; International Collaboration on Endocarditis, Durham, NC; Attikon, Athens, Greece; 4th Department of Internal Medicine, Athens Medical School, Athens, Greece; Hospital Vall D’hebron, Barcelona, Spain; Pontchaillou University Hospital, Rennes, France; Hadassah Medical Center, Jerusalem, Israel; Department of Microbiology and Infectious Diseases Unit, Alfred Hospital, Melbourne, Australia; Infectious Diseases, Barwon Health, Geelong, Australia; Fundación Centro de Estudios Infectológicos, Ciudad Autónoma de Buenos Aires, Argentina; Instituto Cardiovascular de Buenos Aires, Buenos Aires, Argentina; Instituto Nacional de Cardiologia, Rio De Janerio, Brazil
منابع مشابه
Antifungal activity of caspofungin in experimental infective endocarditis caused by Candida albicans
BACKGROUND Infective endocarditis is a disease characterised by heart valve lesions, which exhibit extracellular matrix proteins that act as a physical barrier to prevent the passage of antimicrobial agents. The genus Candida has acquired clinical importance given that it is increasingly being isolated from cases of nosocomial infections. OBJECTIVE To evaluate the activity of caspofungin comp...
متن کاملInfective endocarditis; report from a main referral teaching hospital in Iran
Background/Objective: The aim of the present preliminary study was to assess the demographic, clinical, paraclinical, microbiological, echocardiographic, and therapeutic profile as well as in-hospital outcome of patients with infective endocarditis at a referral center for various infectious diseases in Iran.Methods: Required demographic, clinical, plausible complications and paraclinical data ...
متن کاملInfective endocarditis; report from a main referral teaching hospital in Iran
Background/Objective: The aim of the present preliminary study was to assess the demographic, clinical, paraclinical, microbiological, echocardiographic, and therapeutic profile as well as in-hospital outcome of patients with infective endocarditis at a referral center for various infectious diseases in Iran.Methods: Required demographic, clinical, plausible complications and paraclinical data ...
متن کاملIncidence and Outcome of Documented Fungal Endocarditis
BACKGROUND Fungal endocarditis, the most severe form of infective endocarditis, is characterized by excessive mortality and morbidity. OBJECTIVES The present study aimed to analyze the characteristics of fungal endocarditis to improve the management of these patients. MATERIALS AND METHODS In this cross-sectional study, vegetations on the mitral or tricuspid valves and embolic material surg...
متن کاملCombination therapy with amphotericin B and fluconazole against invasive candidiasis in neutropenic-mouse and infective-endocarditis rabbit models.
Although there are an increasing number of new antifungal agents available, the morbidity and mortality due to invasive mycoses remain high. The high rates of polyene toxicities and the development of azole resistance have raised the issue of using antifungal agents of these classes in combination, despite theoretical concerns regarding antagonism between such agents. This study was designed to...
متن کامل